Anatomy of corpus callosum in prenatally malnourished rats
Biol. Res
; 45(1): 87-92, 2012. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-626752
Biblioteca responsável:
CL1.1
ABSTRACT
The effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old). In the prenatally malnourished animals we observed a significant reduction of the corpus callosum total area, partial areas, and perimeter, as compared with normal animals. In addition, the splenium of corpus callosum (posterior fifth) showed a significant decrease of fiber diameters in the myelinated fibers without changing density. There was also a significant decrease in diameter and a significant increase in density of unmyelinated fibers. Measurements of perimeter's fractal dimensions from sagittal sections of the brain and corpus callosum did not show significant differences between malnourished and control animals. These findings indicate that cortico-cortical connections are vulnerable to the prenatal malnutrition, and suggest this may affect interhemispheric conduction velocity, particulary in visual connections (splenium).
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
/
Corpo Caloso
/
Desnutrição
/
Fibras Nervosas
Aspecto:
Determinantes sociais da saúde
Limite:
Animais
/
Gravidez
Idioma:
Inglês
Revista:
Biol. Res
Assunto da revista:
Biologia
Ano de publicação:
2012
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Chile
/
Espanha
Instituição/País de afiliação:
Pontificia Universidad Católica de Chile/CL
/
Universidad Andrés Bello/CL
/
Universidad de Chile/CL
/
Universidad de Santiago/CL
/
Universidad de Zaragoza/ES