Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama / Influence of nutritional status, hormones serum levels, and family history on breast cancer development
Rev. méd. Chile
; 140(10): 1263-1267, oct. 2012. ilus, tab
Article
em Es
| LILACS
| ID: lil-668698
Biblioteca responsável:
CL1.1
ABSTRACT
Background:
Several studies have analyzed the relation between obesity and the hormonal imbalances generated by overweight and a family history of breast cancer. All of these factors are potentially implicated in the early development of breast cancer.Aim:
To verify the existence of a significant relation between the nutritional status of breast cancer patients, their hormone serum levels (estrogens, prolactin, and progesterone), and the existence of a family history of breast cancer. Material andMethods:
Retrospective data was collected from clinical records of524 women diagnosed with breast cancer in a Spanish hospital.Results:
There was a positive association between estrogen, progesterone and prolactin serum levels and body mass index. The elevations in hormone levels occurred earlier in life among women with a family history of breast cancer. A two way ANOVA found a significant association between progesterone and prolactin levels with the age at diagnosis of breast cancer.Conclusions:
Extreme serum levels of these hormones appear to be related to the early development of breast cancer, which in turn is influenced by the existence of a family history of cancer among those women with normal or average hormone levels.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Progesterona
/
Prolactina
/
Neoplasias da Mama
/
Estado Nutricional
/
Estrogênios
/
Obesidade
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Espanha
País de publicação:
Chile