Lack of association of S100 and neuron-specific enolase with mortality in critically ill patients
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 35(3): 267-270, Jul-Sep. 2013. tab
Artigo
em Inglês
| LILACS
| ID: lil-687944
Biblioteca responsável:
BR1.1
ABSTRACT
Objective:
To evaluate the relationship between brain damage biomarkers and mortality in the intensive care unit (ICU).Methods:
The sample comprised 70 patients admitted to an ICU. Blood samples were collected from all patients on ICU admission, and levels of S100β and neuron-specific enolase (NSE) were determined by ELISA.Results:
Acute Physiologic and Chronic Health Evaluation (APACHE II) score was associated with mortality, but NSE and S100β were not associated with this outcome. In contrast, S100β levels were significantly higher in delirious and non-delirious patients who required mechanical ventilation during ICU stay.Conclusion:
Levels of brain biomarkers at the time of ICU admission did not predict mortality in critically ill patients. .
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Saúde Mental e Transtornos do Comportamento
Base de dados:
LILACS
Assunto principal:
Fosfopiruvato Hidratase
/
Lesões Encefálicas
/
Estado Terminal
/
Delírio
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
National Science and Technology Institute for Translational Medicine/BR
