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[The changes of density of platelet glycoprotein (GP) II b/III a receptor in the perioperative period of gastrectomy in aged rats].
Li, Y F; Wang, S W; Zhao, Y S; Liu, L L; Chen, M Y; Li, B; Feng, B; Yu, S T.
Afiliação
  • Li YF; The Institute of Geriatric Cardiology, The General Hospital of PLA, Beijing 100853, China.
Article em Zh | MEDLINE | ID: mdl-21207711
AIM: To investigate changes of density of platelet glycoprotein (GP) II b/III a receptor in the perioperative period of gastrectomy in aged rats. METHODS: The subtotal gastrectomy operation was performed in 16 adult rats and 16 aged rats respectively. Platelet surface density of GP II b/III receptors were determined by flow cytometric analysis before and 6, 12, 24, 48, 72 hours after operation. RESULTS: 6, 12, 24, 48 and 72 hours after operation, the density of GP II b/III a in aged group increased continuously compared with preoperative period (6h, 12, 72: P < 0.05; 24, 48: P < 0.01). CONCLUSION: Gastrectomy can lead to an increase of density of platelet GP II b/III a receptor in aged rats.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Glicoproteína IIb da Membrana de Plaquetas / Integrina beta3 Limite: Animals Idioma: Zh Revista: Zhongguo Ying Yong Sheng Li Xue Za Zhi Assunto da revista: FISIOLOGIA Ano de publicação: 2001 Tipo de documento: Article País de afiliação: China País de publicação: China
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Glicoproteína IIb da Membrana de Plaquetas / Integrina beta3 Limite: Animals Idioma: Zh Revista: Zhongguo Ying Yong Sheng Li Xue Za Zhi Assunto da revista: FISIOLOGIA Ano de publicação: 2001 Tipo de documento: Article País de afiliação: China País de publicação: China