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Epiretinal membranes in patients with uveitis: morphological and functional analysis with spectral domain optical coherence tomography.
Iannetti, Ludovico; Tortorella, Paolo; D'Ambrosio, Enzo; Spena, Rossela; Zito, Roberta; Gharbiya, Magda.
Afiliação
  • Iannetti L; Department of Ophthalmology, Sapienza University of Rome, 15500161 Rome, Italy ; Servizio di Immunovirologia Oculare, Sapienza Università di Roma, Viale del Policlinico, 15500161 Rome, Italy.
Biomed Res Int ; 2013: 284821, 2013.
Article em En | MEDLINE | ID: mdl-24294602
PURPOSE: To correlate the uveitic epiretinal membrane (ERM) features using spectral-domain optical coherence tomography (SD-OCT) with visual acuity (VA). METHODS: Forty-one eyes of 32 patients were included in this retrospective study. SD-OCT was performed in all patients and data were collected at the time of ERM diagnosis and at the final visit. Both best corrected visual acuity (BCVA) and ERM thickness were correlated with the morphological and clinical features. RESULTS: Final BCVA was positively correlated with male sex (P = 0.0055) and the focal pattern of ERM attachment (P = 0.031) and negatively correlated with IS/OS photoreceptor junction disruption (P = 0.042). BVCA change showed a positive correlation with the age of ERM onset (P = 0.056) but a negative correlation with IS/OS photoreceptor disruption at the ERM diagnosis (P = 0.029) and the increase of central subfield thickness (CST) (P = 0.95). Final ERM thickness correlated with the duration of uveitis (P = 0.0023) and the duration of ERM (P = 1.15 e-05). During the follow-up, ERM thickening correlated with male sex (P = 0.042), posterior uveitis (P = 0.036), uveitis duration (P = 0.026), and broad attachment pattern (P = 0.052). CONCLUSIONS: In the uveitic ERM, VA negatively correlates with IS/OS photoreceptor junction disruption and the increase of CST. ERM thickness is influenced by longer duration of both uveitis and ERM.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Uveíte / Membrana Epirretiniana / Tomografia de Coerência Óptica Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Biomed Res Int Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Uveíte / Membrana Epirretiniana / Tomografia de Coerência Óptica Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Biomed Res Int Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos