Protective effects of melittin on tumor necrosis factor-&#945; induced hepatic damage through suppression of apoptotic pathway and nuclear factor-kappa B activation.

Park, Ji-Hyun; Lee, Woo-Ram; Kim, Hyun-Soo; Han, Sang-Mi; Chang, Young-Chae; Park, Kwan-Kyu

Protective effects of melittin on tumor necrosis factor-α induced hepatic damage through suppression of apoptotic pathway and nuclear factor-kappa B activation.

Park, Ji-Hyun; Lee, Woo-Ram; Kim, Hyun-Soo; Han, Sang-Mi; Chang, Young-Chae; Park, Kwan-Kyu.

Afiliação

Park JH; Department of Pathology, Catholic University of Daegu, College of Medicine, Daegu 705-718, Republic of Korea.
Lee WR; Department of Pathology, Catholic University of Daegu, College of Medicine, Daegu 705-718, Republic of Korea.
Kim HS; Department of Microbiology, Keimyung University, College of Natural Science, Daegu 704-701, Republic of Korea.
Han SM; Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon 441-100, Republic of Korea.
Chang YC; Department of Pathology, Catholic University of Daegu, College of Medicine, Daegu 705-718, Republic of Korea.
Park KK; Department of Pathology, Catholic University of Daegu, College of Medicine, Daegu 705-718, Republic of Korea kkpark@cu.ac.kr.

Exp Biol Med (Maywood) ; 239(12): 1705-14, 2014 Dec.

Article em En | MEDLINE | ID: mdl-24872433

Assuntos

Apoptose; Hepatócitos/efeitos dos fármacos; Fatores Imunológicos/metabolismo; Meliteno/metabolismo; NF-kappa B/antagonistas & inibidores; Fator de Necrose Tumoral alfa/toxicidade; Animais; Linhagem Celular; Dactinomicina/toxicidade; Camundongos

Palavras-chave

Melittin; apoptosis; hepatocyte; nuclear factor-kappa B; tumor necrosis factor-α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Fator de Necrose Tumoral alfa / Apoptose / Hepatócitos / Fatores Imunológicos / Meliteno Limite: Animals Idioma: En Revista: Exp Biol Med (Maywood) Assunto da revista: BIOLOGIA / FISIOLOGIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article

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