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Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.
Wojtal, Kacper A; Cee, Alexandra; Lang, Silvia; Götze, Oliver; Frühauf, Heiko; Geier, Andreas; Pastor-Anglada, Marçal; Torres-Torronteras, Javier; Martí, Ramon; Fried, Michael; Lutz, Thomas A; Maggiorini, Marco; Gassmann, Max; Rogler, Gerhard; Vavricka, Stephan R.
Afiliação
  • Wojtal KA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; kacper.wojtal@yahoo.com.
  • Cee A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland;
  • Lang S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland;
  • Götze O; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; Department of Gastroenterology and Hepatology, University Clinic Würzburg, Würzburg, Germany;
  • Frühauf H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; Division of Gastroenterology and Hepatology, Hospital Triemli, Zurich, Switzerland;
  • Geier A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; Department of Gastroenterology and Hepatology, University Clinic Würzburg, Würzburg, Germany;
  • Pastor-Anglada M; Pharmacology and Experimental Therapeutics, Department of Biochemistry and Molecular Biology, Institute of Biomedicine and Oncology Programme, National Biomedical Research Institute of Liver and Gastrointestinal Disease (CIBER EHD), University of Barcelona, Barcelona, Spain;
  • Torres-Torronteras J; Neuromuscular and Mitochondrial Disorders Unit, and Biomedical Network Research Centre on Rare Diseases (CIBERER), Vall d'Hebron Institut de Recerca, Autonomous University of Barcelona, Barcelona, Spain;
  • Martí R; Neuromuscular and Mitochondrial Disorders Unit, and Biomedical Network Research Centre on Rare Diseases (CIBERER), Vall d'Hebron Institut de Recerca, Autonomous University of Barcelona, Barcelona, Spain;
  • Fried M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland;
  • Lutz TA; Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland; Institute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology (ZIHP), Zurich, Switzerland.
  • Maggiorini M; Intensive Care Unit, Department of Internal Medicine, University of Zurich, Zurich, Switzerland;
  • Gassmann M; Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland; Cayetano Heredia University (UPCH), Lima, Peru; and Zurich Center for Integrative Human Physiology (ZIHP), Zurich, Switzerland.
  • Rogler G; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology (ZIHP), Zurich, Switzerland.
  • Vavricka SR; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; Division of Gastroenterology and Hepatology, Hospital Triemli, Zurich, Switzerland; Zurich Center for Integrative Human Physiology (ZIHP), Zurich, Switzerland.
Am J Physiol Gastrointest Liver Physiol ; 307(7): G673-88, 2014 Oct 01.
Article em En | MEDLINE | ID: mdl-24970780
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Transdução de Sinais / Citocinas / Mediadores da Inflamação / Duodeno / Altitude / Aclimatação / Hipóxia Limite: Humans Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Assunto da revista: FISIOLOGIA / GASTROENTEROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Transdução de Sinais / Citocinas / Mediadores da Inflamação / Duodeno / Altitude / Aclimatação / Hipóxia Limite: Humans Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Assunto da revista: FISIOLOGIA / GASTROENTEROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos