p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/ß-catenin signaling pathway.

Liu, Chunxiao; Zhang, Yanquan; Li, Jun; Wang, Yinyin; Ren, Fangli; Zhou, Yifan; Wu, Yinyuan; Feng, Yarui; Zhou, Yu; Su, Fuqin; Jia, Baoqing; Wang, Dong; Chang, Zhijie

Liu, Chunxiao; Zhang, Yanquan; Li, Jun; Wang, Yinyin; Ren, Fangli; Zhou, Yifan; Wu, Yinyuan; Feng, Yarui; Zhou, Yu; Su, Fuqin; Jia, Baoqing; Wang, Dong; Chang, Zhijie.

Afiliação

Liu C; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B
Zhang Y; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B
Li J; the Department of Immunology, Third Military Medical School, Chongqing 610041, China.
Wang Y; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B
Ren F; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B
Zhou Y; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.
Wu Y; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medi
Feng Y; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B
Zhou Y; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.
Su F; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.
Jia B; the Departments of Surgical Oncology and Pathology, Chinese PLA General Hospital, Beijing 100853, China, and.
Wang D; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B
Chang Z; From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for B

J Biol Chem ; 290(15): 9701-13, 2015 Apr 10.

Article em En | MEDLINE | ID: mdl-25697359

Assuntos

Proteínas de Ciclo Celular/metabolismo; Histona Desacetilase 2/metabolismo; Proteínas Repressoras/metabolismo; Via de Sinalização Wnt; beta Catenina/metabolismo; Acetilação; Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos/genética; Western Blotting; Proteínas de Ciclo Celular/genética; Proliferação de Células/genética; Ciclina D1/genética; Ciclina D1/metabolismo; Expressão Gênica; Células HEK293; Histona Desacetilase 2/genética; Histonas/metabolismo; Humanos; Células MCF-7; Microscopia Confocal; Regiões Promotoras Genéticas/genética; Ligação Proteica; Proteínas Proto-Oncogênicas c-myc/genética; Interferência de RNA; Proteínas Repressoras/genética; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Fator de Transcrição 4; Fatores de Transcrição/genética; beta Catenina/genética

Palavras-chave

Histone Deacetylase (HDAC); Myc (c-Myc); Rprd1A; T-cell Factor (TCF); Wnt Signaling; p15RS; ß-Catenin (B-Catenin)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Proteínas de Ciclo Celular / Beta Catenina / Histona Desacetilase 2 / Via de Sinalização Wnt Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos

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