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Caesarean Section has no impact on lung function at the age of 15 years.
Brüske, Irene; Pei, Zhengcun; Thiering, Elisabeth; Flexeder, Claudia; Berdel, Dietrich; von Berg, Andrea; Koletzko, Sibylle; Bauer, Carl-Peter; Hoffmann, Barbara; Heinrich, Joachim; Schulz, Holger.
Afiliação
  • Brüske I; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environment Health, Neuherberg, Germany.
  • Pei Z; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environment Health, Neuherberg, Germany.
  • Thiering E; Faculty of Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
  • Flexeder C; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environment Health, Neuherberg, Germany.
  • Berdel D; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.
  • von Berg A; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environment Health, Neuherberg, Germany.
  • Koletzko S; Department of Pediatrics, Marienhospital, Wesel, Germany.
  • Bauer CP; Department of Pediatrics, Marienhospital, Wesel, Germany.
  • Hoffmann B; Dr. von Hauner Children's Hospital, Ludwig-Maximilians University of Munich, Munich, Germany.
  • Heinrich J; Department of Pediatrics, Technical University of Munich, Munich, Germany.
  • Schulz H; IUF-Leibniz Research Institute for Environmental Medicine, Germany and Medical Faculty, University of Düsseldorf, Düsseldorf, Germany.
Pediatr Pulmonol ; 50(12): 1262-9, 2015 Dec.
Article em En | MEDLINE | ID: mdl-25847609
BACKGROUND: Epidemiological studies and meta-analyses have shown an increased risk of childhood asthma for children born by Caesarean Section (C-Section). OBJECTIVE: To investigate the effect of delivery by C-Section on lung function and asthma in adolescence in a population-based prospective birth cohort of healthy full term newborns. METHODS: Questionnaire data on mode of delivery and asthma as well as spirometric measurements were available for 1850 adolescents at the age of 15 years, who participated in a follow-up examination of the GINIplus study. Linear regression models were used to examine associations between mode of delivery and lung function parameters. Two reference populations (Lunokid and GLI) were used to calculate the standardized z-scores of lung function parameters. RESULTS: The mean difference in lung function parameters for adolescents born by C-Section, compared to vaginal delivery was not statistically significant. The risk for developing asthma by the age of 15 years was not higher in children born by C-Section-OR: 0.87 (95% CI: 0.57, 1.33) adjusted for sex, age, study center, and parental education level. CONCLUSION: C-Section was not associated with impaired lung function or an increased risk of asthma at the age of 15 years in our birth cohort of healthy full term neonates.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Função Respiratória / Cesárea Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Female / Humans / Male / Pregnancy País/Região como assunto: Europa Idioma: En Revista: Pediatr Pulmonol Assunto da revista: PEDIATRIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Função Respiratória / Cesárea Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Female / Humans / Male / Pregnancy País/Região como assunto: Europa Idioma: En Revista: Pediatr Pulmonol Assunto da revista: PEDIATRIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos