Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells.

Kogel, U; Gonzalez Suarez, I; Xiang, Y; Dossin, E; Guy, P A; Mathis, C; Marescotti, D; Goedertier, D; Martin, F; Peitsch, M C; Hoeng, J

Kogel, U; Gonzalez Suarez, I; Xiang, Y; Dossin, E; Guy, P A; Mathis, C; Marescotti, D; Goedertier, D; Martin, F; Peitsch, M C; Hoeng, J.

Afiliação

Kogel U; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: ulrike.kogel@pmi.com.
Gonzalez Suarez I; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: ignacio.gonzalezSuarez@pmi.com.
Xiang Y; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: yang.xiang@pmi.com.
Dossin E; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: eric.dossin@pmi.com.
Guy PA; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: philippealexandre.guy@pmi.com.
Mathis C; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: carole.mathis@pmi.com.
Marescotti D; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: diego.marescotti@pmi.com.
Goedertier D; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: didier.goedertier@pmi.com.
Martin F; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: florian.martin@pmi.com.
Peitsch MC; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: manuel.peitsch@pmi.com.
Hoeng J; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address: julia.hoeng@pmi.com.

Toxicol In Vitro ; 29(8): 2102-15, 2015 Dec.

Article em En | MEDLINE | ID: mdl-26277032

Assuntos

Aerossóis/efeitos adversos; Células Epiteliais/efeitos dos fármacos; Nicotiana; Mucosa Respiratória/citologia; Fumaça/efeitos adversos; Produtos do Tabaco/efeitos adversos; Brônquios; Linhagem Celular; Sobrevivência Celular/efeitos dos fármacos; Biologia Computacional; Regulação da Expressão Gênica; Humanos; Transcriptoma

Palavras-chave

MRTP; Systems toxicology; in vitro

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumaça / Nicotiana / Aerossóis / Mucosa Respiratória / Células Epiteliais / Produtos do Tabaco Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Toxicol In Vitro Assunto da revista: TOXICOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Reino Unido

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