Enhanced salinomycin production by adjusting the supply of polyketide extender units in Streptomyces albus.

Lu, Chenyang; Zhang, Xiaojie; Jiang, Ming; Bai, Linquan

Lu, Chenyang; Zhang, Xiaojie; Jiang, Ming; Bai, Linquan.

Afiliação

Lu C; State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China; Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhang X; State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China; Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China.
Jiang M; State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China; Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China.
Bai L; State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China; Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic add

Metab Eng ; 35: 129-137, 2016 May.

Article em En | MEDLINE | ID: mdl-26969249

Assuntos

Policetídeos/metabolismo; Piranos/metabolismo; Streptomyces; Acil Coenzima A/genética; Acil Coenzima A/metabolismo; Acil-CoA Desidrogenases/biossíntese; Acil-CoA Desidrogenases/genética; Proteínas de Bactérias/biossíntese; Proteínas de Bactérias/genética; Engenharia Metabólica; Policetídeo Sintases/biossíntese; Policetídeo Sintases/genética; Streptomyces/genética; Streptomyces/metabolismo

Palavras-chave

Crotonyl-CoA reductase; Extender unit; Genome; Polyketide; Salinomycin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piranos / Streptomyces / Policetídeos Idioma: En Revista: Metab Eng Assunto da revista: ENGENHARIA BIOMEDICA / METABOLISMO Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Bélgica

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