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Effect of green light spectra on the reduction of retinal damage and stress in goldfish, Carassius auratus.
Song, Jin Ah; Kim, Na Na; Choi, Young Jae; Choi, Cheol Young.
Afiliação
  • Song JA; Division of Marine BioScience, Korea Maritime and Ocean University, Busan, 49112, Republic of Korea.
  • Kim NN; Division of Marine BioScience, Korea Maritime and Ocean University, Busan, 49112, Republic of Korea.
  • Choi YJ; Division of Marine BioScience, Korea Maritime and Ocean University, Busan, 49112, Republic of Korea.
  • Choi CY; Division of Marine BioScience, Korea Maritime and Ocean University, Busan, 49112, Republic of Korea. Electronic address: choic@kmou.ac.kr.
Biochem Biophys Res Commun ; 476(2): 96-101, 2016 07 22.
Article em En | MEDLINE | ID: mdl-27181352
We investigated the effect of light spectra on retinal damage and stress in goldfish using green (530 nm) and red (620 nm) light emitting diodes (LEDs) at three intensities each (0.5, 1.0, and 1.5 W/m(2)). We measured the change in the levels of plasma cortisol and H2O2 and expression and levels of caspase-3. The apoptotic response of green and red LED spectra was assessed using the terminal transferase dUTP nick end labeling (TUNEL) assay. Stress indicator (cortisol and H2O2) and apoptosis-related genes (caspase-3) decreased in green light, but increased in red light with higher light intensities over time. The TUNEL assay revealed that more apoptotic cells were detected in outer nuclear layers after exposure to red LED over time with the increase in light intensity, than the other spectra. These results indicate that green light efficiently reduces retinal damage and stress, whereas red light induces it. Therefore, red light-induced retina damage may induce apoptosis in goldfish retina.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Estresse Fisiológico / Carpa Dourada / Apoptose Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Estresse Fisiológico / Carpa Dourada / Apoptose Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos