Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder.

Luna, Ruth Ann; Oezguen, Numan; Balderas, Miriam; Venkatachalam, Alamelu; Runge, Jessica K; Versalovic, James; Veenstra-VanderWeele, Jeremy; Anderson, George M; Savidge, Tor; Williams, Kent C

Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder.

Luna, Ruth Ann; Oezguen, Numan; Balderas, Miriam; Venkatachalam, Alamelu; Runge, Jessica K; Versalovic, James; Veenstra-VanderWeele, Jeremy; Anderson, George M; Savidge, Tor; Williams, Kent C.

Afiliação

Luna RA; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Oezguen N; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Balderas M; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Venkatachalam A; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Runge JK; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Versalovic J; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Veenstra-VanderWeele J; Department of Psychiatry, Columbia University, New York, New York.
Anderson GM; Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
Savidge T; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.
Williams KC; Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Nationwide Children's Hospital, Columbus, Ohio.

Cell Mol Gastroenterol Hepatol ; 3(2): 218-230, 2017 Mar.

Article em En | MEDLINE | ID: mdl-28275689

Palavras-chave

5-HIAA, 5-hydroxyindoleacetic acid; 5-HT, serotonin; ASD, autism spectrum disorder; FGID, functional gastrointestinal disorder; GI, gastrointestinal; GM-CSF, granulocyte-macrophage colony-stimulating factor; GROα, growth-related oncogene alpha; Gastrointestinal Disorders; IBS, irritable bowel syndrome; IFN, interferon; IL, interleukin; IP, interferon gamma-induced protein; MCP-1, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; Microbiome; MicrobiomeGutBrain Axis; Mucosa; NT, neurotypical; OTU, operational taxonomic unit; QPGS-RIII, Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III; Serotonin; TNF, tumor necrosis factor; VEGF, vascular endothelial growth factor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Cell Mol Gastroenterol Hepatol Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos

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