TP53 alterations in Wilms tumour represent progression events with strong intratumour heterogeneity that are closely linked but not limited to anaplasia.

Wegert, Jenny; Vokuhl, Christian; Ziegler, Barbara; Ernestus, Karen; Leuschner, Ivo; Furtwängler, Rhoikos; Graf, Norbert; Gessler, Manfred

Wegert, Jenny; Vokuhl, Christian; Ziegler, Barbara; Ernestus, Karen; Leuschner, Ivo; Furtwängler, Rhoikos; Graf, Norbert; Gessler, Manfred.

Afiliação

Wegert J; Theodor-Boveri-Institute/Biocenter, Developmental BiochemistryWuerzburg UniversityWuerzburgGermany.
Vokuhl C; Department of Pathology, Kiel Paediatric Cancer RegistryChristian Albrechts UniversityKielGermany.
Ziegler B; Theodor-Boveri-Institute/Biocenter, Developmental BiochemistryWuerzburg UniversityWuerzburgGermany.
Ernestus K; Institute for PathologyWuerzburg UniversityWuerzburgGermany.
Leuschner I; Department of Pathology, Kiel Paediatric Cancer RegistryChristian Albrechts UniversityKielGermany.
Furtwängler R; Department of Pediatric Oncology and HematologySaarland University HospitalHomburgGermany.
Graf N; Department of Pediatric Oncology and HematologySaarland University HospitalHomburgGermany.
Gessler M; Theodor-Boveri-Institute/Biocenter, Developmental BiochemistryWuerzburg UniversityWuerzburgGermany.

J Pathol Clin Res ; 3(4): 234-248, 2017 Oct.

Article em En | MEDLINE | ID: mdl-29085664

Palavras-chave

TP53; Wilms tumour; anaplasia; nephroblastoma; tumour heterogeneity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: J Pathol Clin Res Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

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