Insights into the inhibitory mechanism of triazole-based small molecules on phosphatidylinositol-4,5-bisphosphate binding pleckstrin homology domain.

Gorai, Sukhamoy; Bagdi, Prasanta Ray; Borah, Rituparna; Paul, Debasish; Santra, Manas Kumar; Khan, Abu Taleb; Manna, Debasis

Gorai, Sukhamoy; Bagdi, Prasanta Ray; Borah, Rituparna; Paul, Debasish; Santra, Manas Kumar; Khan, Abu Taleb; Manna, Debasis.

Afiliação

Gorai S; Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India.
Bagdi PR; Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India.
Borah R; Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India.
Paul D; National Center for Cell Science, Pune 411007, Maharashtra, India.
Santra MK; National Center for Cell Science, Pune 411007, Maharashtra, India.
Khan AT; Alia University, DN 18, 8th Floor, Sector V, Kolkata 700091, India.
Manna D; Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India.

Biochem Biophys Rep ; 2: 75-86, 2015 Jul.

Article em En | MEDLINE | ID: mdl-29124147

Palavras-chave

1,2,3-Triazol-4-yl methanol substituent; Cellular displacement assay; Inhibition of proteinlipid interactions; Phosphatidylinositols; Pleckstrin homology domains; Surface plasmon resonance-based competitive binding assay

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Índia País de publicação: Holanda

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