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Role of quantitative analysis of T2 relaxation time in differentiating benign from malignant breast lesions.
Liu, Li; Yin, Bo; Shek, Kawai; Geng, Daoying; Lu, Yiping; Wen, Jianbo; Kuai, Xinping; Peng, Weijun.
Afiliação
  • Liu L; 1 Department of Radiology, 162765 Fudan University Shanghai Cancer Centre, Shanghai, China; Department of Oncology , Shanghai Medical College, Fudan University, Shanghai, China.
  • Yin B; 2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
  • Shek K; 3 Department of Radiology, Queen Elizabeth Hospital, Hong Kong.
  • Geng D; 2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
  • Lu Y; 2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
  • Wen J; 2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
  • Kuai X; 2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
  • Peng W; 1 Department of Radiology, 162765 Fudan University Shanghai Cancer Centre, Shanghai, China; Department of Oncology , Shanghai Medical College, Fudan University, Shanghai, China.
J Int Med Res ; 46(5): 1928-1935, 2018 May.
Article em En | MEDLINE | ID: mdl-29557239
Objective To investigate the role of quantitative analysis of T2 relaxation time in the magnetic resonance imaging (MRI) diagnosis of breast cancer. Methods The study enrolled patients with clinical breast masses who were examined using MRI at eight different echo times. The differences in T2 relaxation time of benign and malignant breast lesions were analysed. Results A total of 67 patients (67 breast lesions: 46 malignant, 21 benign) were examined. The mean ± SD T2 relaxation time was significantly lower in the 46 malignant lesions compared with the 21 benign lesions (82.69 ± 15.37 ms versus 95.48 ± 26.51 ms, respectively). The area under the curve was 0.731. Using 79.52 ms as the cut-off between benign and malignant breast lesions, a sensitivity of 85.7% and a specificity of 58.7% were obtained. Conclusions There was a significant difference in T2 relaxation time between benign and malignant breast lesions. The specificity of using T2 relaxation time alone for the differentiation of benign from malignant lesions was not high, but it could constitute a new adjunct in the MRI diagnosis of breast cancer.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Imageamento por Ressonância Magnética Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: J Int Med Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Imageamento por Ressonância Magnética Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: J Int Med Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido