Recurrently Mutated Genes Differ between Leptomeningeal and Solid Lung Cancer Brain Metastases.

Li, Yingmei; Liu, Boxiang; Connolly, Ian David; Kakusa, Bina Wasunga; Pan, Wenying; Nagpal, Seema; Montgomery, Stephen B; Hayden Gephart, Melanie

Li, Yingmei; Liu, Boxiang; Connolly, Ian David; Kakusa, Bina Wasunga; Pan, Wenying; Nagpal, Seema; Montgomery, Stephen B; Hayden Gephart, Melanie.

Afiliação

Li Y; Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Liu B; Department of Biology, Stanford University School of Medicine, Stanford, California; Department of Pathology, Stanford University School of Medicine, Stanford, California; Department of Genetics, Stanford University, Stanford, California.
Connolly ID; Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Kakusa BW; Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Pan W; Department of Bioengineering, Stanford University, Stanford, California.
Nagpal S; Department of Neurology, Stanford University School of Medicine, Stanford, California.
Montgomery SB; Department of Pathology, Stanford University School of Medicine, Stanford, California; Department of Genetics, Stanford University, Stanford, California.
Hayden Gephart M; Department of Neurosurgery, Stanford University School of Medicine, Stanford, California. Electronic address: mghayden@stanford.edu.

J Thorac Oncol ; 13(7): 1022-1027, 2018 07.

Article em En | MEDLINE | ID: mdl-29604399

Assuntos

Neoplasias Encefálicas/secundário; Neoplasias Meníngeas/patologia; Mutação; Neoplasias/patologia; Proteínas Proto-Oncogênicas p21(ras)/genética; Proteína Supressora de Tumor p53/genética; Biomarcadores Tumorais/genética; Neoplasias Encefálicas/genética; Receptores ErbB/genética; Seguimentos; Humanos; Neoplasias Meníngeas/genética; Neoplasias/genética; Prognóstico; Estudos Retrospectivos; Taxa de Sobrevida

Palavras-chave

EGFR; KRAS; Leptomeningeal metastases; Nonsmall cell lung cancer; Whole exome sequencing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas p21(ras) / Neoplasias Meníngeas / Mutação / Neoplasias Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Thorac Oncol Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos

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