A Crude 1-DNJ Extract from Home Made Bombyx Batryticatus Inhibits Diabetic Cardiomyopathy-Associated Fibrosis in db/db Mice and Reduces Protein <i>N</i>-Glycosylation Levels.

Zhao, Qing; Jia, Tian Zhu; Cao, Qi Chen; Tian, Fang; Ying, Wan Tao

A Crude 1-DNJ Extract from Home Made Bombyx Batryticatus Inhibits Diabetic Cardiomyopathy-Associated Fibrosis in db/db Mice and Reduces Protein N-Glycosylation Levels.

Zhao, Qing; Jia, Tian Zhu; Cao, Qi Chen; Tian, Fang; Ying, Wan Tao.

Afiliação

Zhao Q; The Key Laboratory of Chinese Materia Medica Processing Principle Analysis of the State Administration of Traditional Chinese Medicine, Pharmaceutical College of Liaoning Traditional Chinese Medicine University, Chinese Materia Medica Processing Engineering Technology Research Center of Liaoning Pro
Jia TZ; Chinese Materia Medica Department, Traditional Chinese Medicine College of Hebei University, Baoding 071000, China. wshxr2003@163.com.
Cao QC; Beijing Institute of Lifeomics, Beijing Proteome Research Center, Beijing 102206, China. wshxr2003@163.com.
Tian F; The Key Laboratory of Chinese Materia Medica Processing Principle Analysis of the State Administration of Traditional Chinese Medicine, Pharmaceutical College of Liaoning Traditional Chinese Medicine University, Chinese Materia Medica Processing Engineering Technology Research Center of Liaoning Pro
Ying WT; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China. cao_qc@tib.cas.cn.

Int J Mol Sci ; 19(6)2018 Jun 07.

Article em En | MEDLINE | ID: mdl-29880742

Assuntos

1-Desoxinojirimicina/farmacologia; Bombyx/química; Cardiomiopatias Diabéticas/metabolismo; Cardiomiopatias Diabéticas/patologia; 1-Desoxinojirimicina/química; Animais; Biomarcadores; Cardiomiopatias Diabéticas/tratamento farmacológico; Modelos Animais de Doenças; Fibrose; Glicosilação; Camundongos; Miocárdio/metabolismo; Miocárdio/patologia; Polissacarídeos; Proteoma

Palavras-chave

1-DNJ; N-glycosylation; diabetic cardiomyopathy; fibrosis; α-1,6-fucosylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bombyx / 1-Desoxinojirimicina / Cardiomiopatias Diabéticas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2018 Tipo de documento: Article País de publicação: Suíça

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