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Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters.
Xu, Jian; Cen, Yixin; Singh, Warispreet; Fan, Jiajie; Wu, Lian; Lin, Xianfu; Zhou, Jiahai; Huang, Meilan; Reetz, Manfred T; Wu, Qi.
Afiliação
  • Xu J; Department of Chemistry , Zhejiang University , Hangzhou 310027 , PR China.
  • Cen Y; Department of Chemistry , Zhejiang University , Hangzhou 310027 , PR China.
  • Singh W; State Key Laboratory of Bio-organic and Natural Products Chemistry , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , Shanghai 200032 , PR China.
  • Fan J; School of Chemistry and Chemical Engineering , Queen's University , David Keir Building, Stranmillis Road , Belfast BT9 5AG , Northern Ireland , U.K.
  • Wu L; Department of Chemistry , Zhejiang University , Hangzhou 310027 , PR China.
  • Lin X; State Key Laboratory of Bio-organic and Natural Products Chemistry , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , Shanghai 200032 , PR China.
  • Zhou J; Department of Chemistry , Zhejiang University , Hangzhou 310027 , PR China.
  • Huang M; State Key Laboratory of Bio-organic and Natural Products Chemistry , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , Shanghai 200032 , PR China.
  • Reetz MT; School of Chemistry and Chemical Engineering , Queen's University , David Keir Building, Stranmillis Road , Belfast BT9 5AG , Northern Ireland , U.K.
  • Wu Q; Max-Planck-Institut für Kohlenforschung , Kaiser-Wilhelm-Platz 1 , 45470 Mülheim an der Ruhr , Germany.
J Am Chem Soc ; 141(19): 7934-7945, 2019 05 15.
Article em En | MEDLINE | ID: mdl-31023008

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Fúngicas / Engenharia de Proteínas / Ésteres / Lipase Idioma: En Revista: J Am Chem Soc Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Fúngicas / Engenharia de Proteínas / Ésteres / Lipase Idioma: En Revista: J Am Chem Soc Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos