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Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Cen, Yixin; Singh, Warispreet; Arkin, Mamatjan; Moody, Thomas S; Huang, Meilan; Zhou, Jiahai; Wu, Qi; Reetz, Manfred T.
Afiliação
  • Cen Y; Department of Chemistry, Zhejiang University, 310027, Hangzhou, China.
  • Singh W; State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 200032, Shanghai, China.
  • Arkin M; School of Chemistry and Chemical Engineering, Queen's University, Belfast, Northern Ireland, BT9 5AG, UK.
  • Moody TS; Department of Biocatalysis and Isotope Chemistry, Almac Sciences, Craigavon, Northern Ireland, BT63 5QD, UK.
  • Huang M; Department of Chemistry, Zhejiang University, 310027, Hangzhou, China.
  • Zhou J; Department of Biocatalysis and Isotope Chemistry, Almac Sciences, Craigavon, Northern Ireland, BT63 5QD, UK.
  • Wu Q; School of Chemistry and Chemical Engineering, Queen's University, Belfast, Northern Ireland, BT9 5AG, UK. m.huang@qub.ac.uk.
  • Reetz MT; State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 200032, Shanghai, China. jiahai@mail.sioc.ac.cn.
Nat Commun ; 10(1): 3198, 2019 07 19.
Article em En | MEDLINE | ID: mdl-31324776
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína / Lipase Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína / Lipase Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido