Discovery of N-(4-fluoro-2-(phenylamino)phenyl)-pyrazole-4-carboxamides as potential succinate dehydrogenase inhibitors.

Zhang, Aigui; Yue, Ying; Yang, Yihua; Yang, Jian; Tao, Ke; Jin, Hong; Hou, Taiping

Zhang, Aigui; Yue, Ying; Yang, Yihua; Yang, Jian; Tao, Ke; Jin, Hong; Hou, Taiping.

Afiliação

Zhang A; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China.
Yue Y; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China.
Yang Y; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China.
Yang J; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China.
Tao K; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China.
Jin H; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China. Electronic address: jinhong@scu.edu.cn.
Hou T; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, PR China. Electronic address: houtplab@scu.edu.cn.

Pestic Biochem Physiol ; 158: 175-184, 2019 Jul.

Article em En | MEDLINE | ID: mdl-31378354

Assuntos

Antifúngicos/química; Antifúngicos/farmacologia; Succinato Desidrogenase/metabolismo; Alternaria/efeitos dos fármacos; Alternaria/enzimologia; Ascomicetos/efeitos dos fármacos; Ascomicetos/enzimologia; Fusarium/efeitos dos fármacos; Fusarium/enzimologia; Phytophthora infestans/efeitos dos fármacos; Phytophthora infestans/enzimologia; Rhizoctonia/efeitos dos fármacos; Rhizoctonia/enzimologia; Relação Estrutura-Atividade

Palavras-chave

Antifungal activities; Molecular modeling; Pyrazole-4-carboxamides; Succinate dehydrogenase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Succinato Desidrogenase / Antifúngicos Idioma: En Revista: Pestic Biochem Physiol Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

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