A Novel Peptide Ameliorates LPS-Induced Intestinal Inflammation and Mucosal Barrier Damage via Its Antioxidant and Antiendotoxin Effects.

Zhang, Lulu; Wei, Xubiao; Zhang, Rijun; Si, Dayong; Petitte, James N; Ahmad, Baseer; Zhang, Manyi

Zhang, Lulu; Wei, Xubiao; Zhang, Rijun; Si, Dayong; Petitte, James N; Ahmad, Baseer; Zhang, Manyi.

Afiliação

Zhang L; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Wei X; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Zhang R; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. rjzhang@cau.edu.cn.
Si D; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Petitte JN; Prestage Department of Poultry Science, North Carolina State University, Raleigh, NC 27695, USA.
Ahmad B; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Zhang M; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Int J Mol Sci ; 20(16)2019 Aug 15.

Article em En | MEDLINE | ID: mdl-31443263

Assuntos

Antioxidantes/uso terapêutico; Inflamação/induzido quimicamente; Inflamação/tratamento farmacológico; Mucosa Intestinal/metabolismo; Lipopolissacarídeos/toxicidade; Animais; Interleucina-6/metabolismo; Mucosa Intestinal/efeitos dos fármacos; Camundongos; NF-kappa B/metabolismo; Ocludina/metabolismo; Células RAW 264.7; Transdução de Sinais/efeitos dos fármacos; Proteína da Zônula de Oclusão-1/metabolismo

Palavras-chave

Intestinal barrier; NF-κB; anti-inflammatory activity; anti-oxidation; lipopolysaccharide neutralization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Inflamação / Mucosa Intestinal / Antioxidantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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