Systems biology based drug repositioning for development of cancer therapy.

Turanli, Beste; Altay, Ozlem; Borén, Jan; Turkez, Hasan; Nielsen, Jens; Uhlen, Mathias; Arga, Kazim Yalcin; Mardinoglu, Adil

Turanli, Beste; Altay, Ozlem; Borén, Jan; Turkez, Hasan; Nielsen, Jens; Uhlen, Mathias; Arga, Kazim Yalcin; Mardinoglu, Adil.

Afiliação

Turanli B; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-17121, Sweden; Department of Bioengineering, Marmara University, Istanbul, Turkey; Department of Bioengineering, Istanbul Medeniyet University, Istanbul, Turkey.
Altay O; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-17121, Sweden.
Borén J; Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital Gothenburg, Sweden.
Turkez H; Department of Molecular Biology and Genetics, Erzurum Technical University, Erzurum 25240, Turkey.
Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Uhlen M; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-17121, Sweden.
Arga KY; Department of Bioengineering, Marmara University, Istanbul, Turkey.
Mardinoglu A; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-17121, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, United Kingdom. Electronic address: adilm@scilifelab.se.

Semin Cancer Biol ; 68: 47-58, 2021 01.

Article em En | MEDLINE | ID: mdl-31568815

Assuntos

Antineoplásicos/uso terapêutico; Biologia Computacional/métodos; Descoberta de Drogas; Reposicionamento de Medicamentos/métodos; Neoplasias/tratamento farmacológico; Biologia de Sistemas/métodos; Animais; Humanos

Palavras-chave

Cancer; Drug repositioning; Network-based approaches; Signature-based approaches; Systems biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biologia Computacional / Biologia de Sistemas / Descoberta de Drogas / Reposicionamento de Medicamentos / Neoplasias / Antineoplásicos Aspecto: Patient_preference Limite: Animals / Humans Idioma: En Revista: Semin Cancer Biol Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Turquia País de publicação: Reino Unido

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