IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.

Zhang, Jingzi; Zhao, Ruoyu; Yu, Clinton; Bryant, Christine L N; Wu, Kenneth; Liu, Zhihong; Ding, Yibing; Zhao, Yue; Xue, Bin; Pan, Zhen-Qiang; Li, Chaojun; Huang, Lan; Fang, Lei

Zhang, Jingzi; Zhao, Ruoyu; Yu, Clinton; Bryant, Christine L N; Wu, Kenneth; Liu, Zhihong; Ding, Yibing; Zhao, Yue; Xue, Bin; Pan, Zhen-Qiang; Li, Chaojun; Huang, Lan; Fang, Lei.

Afiliação

Zhang J; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.
Zhao R; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.
Yu C; Department of Physiology and Biophysics, University of California, Irvine, California 92697, Unites States.
Bryant CLN; Department of Physiology and Biophysics, University of California, Irvine, California 92697, Unites States.
Wu K; Department of Oncological Sciences, Mount Sinai School of Medicine, New York, New York 10029, United States.
Liu Z; School of Life Science, Nanjing University, Nanjing 210023, China.
Ding Y; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.
Zhao Y; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.
Xue B; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.
Pan ZQ; Department of Oncological Sciences, Mount Sinai School of Medicine, New York, New York 10029, United States.
Li C; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.
Huang L; Department of Physiology and Biophysics, University of California, Irvine, California 92697, Unites States.
Fang L; Medical School and Model Animal Research Center of Nanjing University, Nanjing 210093, China.

J Proteome Res ; 19(3): 1119-1130, 2020 03 06.

Article em En | MEDLINE | ID: mdl-31950832

Assuntos

NF-kappa B; Transdução de Sinais; Complexo do Signalossomo COP9/genética; Complexo do Signalossomo COP9/metabolismo; NF-kappa B/genética; NF-kappa B/metabolismo; Peptídeo Hidrolases/genética; Peptídeo Hidrolases/metabolismo; Fosforilação

Palavras-chave

COP9 signalosome; CSN5; IKK complex; NF-κB signaling pathway; TNF-α; deneddylation; phosphorylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / NF-kappa B Idioma: En Revista: J Proteome Res Assunto da revista: BIOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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