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Discovery of tofacitinib derivatives as orally active antitumor agents based on the scaffold hybridization strategy.
Shi, Xiao-Jing; Wang, Shuai; Li, Xiao-Jing; Yuan, Xiao-Han; Cao, Li-Juan; Yu, Bin; Liu, Hong-Min.
Afiliação
  • Shi XJ; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China.
  • Wang S; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129, USA.
  • Li XJ; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China.
  • Yuan XH; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China.
  • Cao LJ; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China.
  • Yu B; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210023, China. Electronic address: zzuyubin@hotma
  • Liu HM; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Military of Education, Zhengzhou University, Zhengzhou 450001, China. Electronic address: liuhm@zzu.edu.cn.
Eur J Med Chem ; 203: 112601, 2020 Oct 01.
Article em En | MEDLINE | ID: mdl-32682202
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Pirimidinas / Desenho de Fármacos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Pirimidinas / Desenho de Fármacos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: França