LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.

Shi, Wen-Jing; Liu, Hao; Ge, Ya-Fang; Wu, Dan; Tan, Ya-Jing; Shen, Yu-Chen; Wang, Huihui; Xu, Han

Shi, Wen-Jing; Liu, Hao; Ge, Ya-Fang; Wu, Dan; Tan, Ya-Jing; Shen, Yu-Chen; Wang, Huihui; Xu, Han.

Afiliação

Shi WJ; Department of Clinical Laboratory, International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200030,China; The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shangha
Liu H; Department of Health Technology and Informnatics, Hong Kong Polytechnic University, 999077, Hong Kong Special Administrative Region.
Ge YF; Department of Clinical Laboratory, International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200030,China.
Wu D; Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China; The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;
Tan YJ; Center of Reproductive Medicine, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shen YC; Department of Clinical Laboratory, International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200030,China.
Wang H; Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.
Xu H; Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.

Cytokine ; 136: 155286, 2020 12.

Article em En | MEDLINE | ID: mdl-32950808

Assuntos

MicroRNAs/biossíntese; PTEN Fosfo-Hidrolase/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA Longo não Codificante/metabolismo; RNA Neoplásico/metabolismo; Transdução de Sinais; Neoplasias do Colo do Útero/metabolismo; Animais; Feminino; Células HeLa; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; MicroRNAs/genética; PTEN Fosfo-Hidrolase/genética; Fosfatidilinositol 3-Quinases/genética; Proteínas Proto-Oncogênicas c-akt/genética; RNA Longo não Codificante/genética; RNA Neoplásico/genética; Neoplasias do Colo do Útero/genética; Neoplasias do Colo do Útero/patologia

Palavras-chave

Cell proliferation; Cervical cancer; LINC00673; Tumor prognosis; miR-126-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Neoplásico / Transdução de Sinais / Neoplasias do Colo do Útero / Fosfatidilinositol 3-Quinases / MicroRNAs / PTEN Fosfo-Hidrolase / Proteínas Proto-Oncogênicas c-akt / RNA Longo não Codificante Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Cytokine Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2020 Tipo de documento: Article

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