Predicting favorable landing pads for targeted integrations in Chinese hamster ovary cell lines by learning stability characteristics from random transgene integrations.

Dhiman, Heena; Campbell, Marguerite; Melcher, Michael; Smith, Kevin D; Borth, Nicole

Dhiman, Heena; Campbell, Marguerite; Melcher, Michael; Smith, Kevin D; Borth, Nicole.

Afiliação

Dhiman H; University of Natural Resources and Life Sciences, Vienna, Austria.
Campbell M; Austrian Centre of Industrial Biotechnology, Vienna, Austria.
Melcher M; Janssen Research & Development, PA, USA.
Smith KD; University of Natural Resources and Life Sciences, Vienna, Austria.
Borth N; Janssen Research & Development, PA, USA.

Comput Struct Biotechnol J ; 18: 3632-3648, 2020.

Article em En | MEDLINE | ID: mdl-33304461

Palavras-chave

Chinese hamster ovary cells; Genomics; Integration sites; Stable transgene expression; Transcriptomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Comput Struct Biotechnol J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Áustria País de publicação: Holanda

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