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A New Approach for the Production of Selenium-Enriched and Probiotic Yeast Biomass from Agro-Industrial by-Products in a Stirred-Tank Bioreactor.
Martiniano, Sabrina Evelin; Fernandes, Letícia Alves; Alba, Edith Mier; Philippini, Rafael Rodrigues; Tabuchi, Stephanie Caroline Tavares; Kieliszek, Marek; Santos, Júlio César Dos; da Silva, Silvio Silvério.
Afiliação
  • Martiniano SE; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
  • Fernandes LA; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
  • Alba EM; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
  • Philippini RR; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
  • Tabuchi SCT; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
  • Kieliszek M; Department of Food Biotechnology and Microbiology, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, 02-776 Warsaw, Poland.
  • Santos JCD; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
  • da Silva SS; Engineering School of Lorena, University of São Paulo, Lorena 12.602-810, SP, Brazil.
Metabolites ; 10(12)2020 Dec 13.
Article em En | MEDLINE | ID: mdl-33322101
The production of biomolecules using agro-industrial by-products as feedstock is a growing trend worldwide. Selenium (Se) is a trace element essential for health, and the Se-enrichment of yeast biomass can enhance its benefits. This study investigated the feasibility of the production of Saccharomyces cerevisiae Se-enriched biomass using a medium composed of corn bran and soybean bran acid hydrolysates as carbon and nitrogen sources in a stirred-tank reactor. After hydrolysis, hydrolysates presented complex composition and high concentrations of sugars, proteins, and minerals. The use of a stirred-tank bioreactor leads to the production of 9 g/L S. cerevisiae biomass enriched with 236.93 µg/g Se, and 99% cell viability. Likewise, the combination of sugarcane molasses and soybean bran hydrolysate was effective for cell growth of a probiotic strain of S. cerevisiae with a 24.08% ß-glucan content. The results demonstrated that starchy acid hydrolysates are low-cost and efficient substrates for the production of yeast biomass and derivate products and may contribute to further studies for a sustainable development of biorefinery technologies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Metabolites Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Metabolites Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça