Population Pharmacokinetic Modelling and Simulation to Determine the Optimal Dose of Nanoparticulated Sorafenib to the Reference Sorafenib.

Huh, Ki Young; Hwang, Sejung; Park, Sang Yeob; Lim, Hye Jung; Jin, Miryung; Oh, Jaeseong; Yu, Kyung Sang; Chung, Jae Yong

Huh, Ki Young; Hwang, Sejung; Park, Sang Yeob; Lim, Hye Jung; Jin, Miryung; Oh, Jaeseong; Yu, Kyung Sang; Chung, Jae Yong.

Afiliação

Huh KY; Department of Clinical Pharmacology and Therapeutics, College of Medicine and Hospital, Seoul National University, Seoul 03080, Korea.
Hwang S; Department of Clinical Pharmacology and Therapeutics, College of Medicine and Hospital, Seoul National University, Seoul 03080, Korea.
Park SY; Samyang Biopharmaceuticals Corp., Gyeonggi-do 13488, Korea.
Lim HJ; Samyang Biopharmaceuticals Corp., Gyeonggi-do 13488, Korea.
Jin M; Samyang Biopharmaceuticals Corp., Gyeonggi-do 13488, Korea.
Oh J; Department of Clinical Pharmacology and Therapeutics, College of Medicine and Hospital, Seoul National University, Seoul 03080, Korea.
Yu KS; Department of Clinical Pharmacology and Therapeutics, College of Medicine and Hospital, Seoul National University, Seoul 03080, Korea.
Chung JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Bundang Hospital, Gyeonggi-do 13620, Korea.

Pharmaceutics ; 13(5)2021 Apr 28.

Article em En | MEDLINE | ID: mdl-33925058

Palavras-chave

bioavailability; enterohepatic reabsorption; pharmacokinetics; pharmacometrics; sorafenib

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Prognostic_studies Idioma: En Revista: Pharmaceutics Ano de publicação: 2021 Tipo de documento: Article País de publicação: Suíça

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