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Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion.
Wu, Jing; Han, Yi; Yang, Ling; Liu, Zhaoping.
Afiliação
  • Wu J; Department of Anesthesiology, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, Shaanxi, PR China.
  • Han Y; Department of Anesthesiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, PR China.
  • Yang L; Department of Gynecology, Qingdao West Coast New Area Central Hospital, Shandong Province, PR China.
  • Liu Z; Department of Obstetrics and Gynecology, Qingdao West Coast New Area Central Hospital, Qingdao, Shandong Province, PR China.
Pak J Pharm Sci ; 34(3(Special)): 1249-1254, 2021 May.
Article em En | MEDLINE | ID: mdl-34602396
This study attempted to investigate the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on painless induced abortion. A total of 82 pregnant females were divided into study group and reference group. The subjects in the study group took seaweed polysaccharides orally before surgery and received intravenous anesthesia with dexmedetomidine and propofol, while the subjects in the reference group received intravenous anesthesia with sufentanil combined with propofol. The onset time of anesthesia in the reference group was significantly shorter than that in the study group (P<0.001) and both recovery time and the dosage of propofol in the study group were significantly lower than those in the reference group (P<0.001). The values of MAP and HR at T3 and T4, clinical analgesia effective rate, ramsay sedation scores and incidence of adverse reactions of the subjects in study group was significantly better than those indexes of the subjects in reference group (P<0.05). The intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides is a promising strategy for painless induced abortion, which is worthy of application and popularization in clinical practice.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carragenina / Propofol / Aborto Induzido / Anestésicos Intravenosos / Dexmedetomidina / Sedação Profunda / Dor Processual Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Paquistão
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carragenina / Propofol / Aborto Induzido / Anestésicos Intravenosos / Dexmedetomidina / Sedação Profunda / Dor Processual Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Paquistão