Direct Delivery of ANA-TA9, a Peptide Capable of Aß Hydrolysis, to the Brain by Intranasal Administration.

Hatakawa, Yusuke; Tanaka, Akiko; Furubayashi, Tomoyuki; Nakamura, Rina; Konishi, Motomi; Akizawa, Toshifumi; Sakane, Toshiyasu

Hatakawa, Yusuke; Tanaka, Akiko; Furubayashi, Tomoyuki; Nakamura, Rina; Konishi, Motomi; Akizawa, Toshifumi; Sakane, Toshiyasu.

Afiliação

Hatakawa Y; Laboratory of Bio-Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba, Sendai 980-8578, Japan.
Tanaka A; Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Motoyamakita-Machi 4-19-1 Higashinada, Kobe, Hyogo 658-8558, Japan.
Furubayashi T; Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Motoyamakita-Machi 4-19-1 Higashinada, Kobe, Hyogo 658-8558, Japan.
Nakamura R; O-Force Co., Ltd., 3454 Irino Kuroshio-Cho, Hata-Gun, Kochi 789-1931, Japan.
Konishi M; Laboratory of Pharmacology, School of Medicine, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan.
Akizawa T; Department of Integrative Pharmaceutical Science, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka 573-0101, Japan.
Sakane T; O-Force Co., Ltd., 3454 Irino Kuroshio-Cho, Hata-Gun, Kochi 789-1931, Japan.

Pharmaceutics ; 13(10)2021 Oct 13.

Article em En | MEDLINE | ID: mdl-34683967

Palavras-chave

Alzheimer's disease; Catalytide; nasal application; nose to brain; olfactory pathway; synthetic peptide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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