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Dictamnine, a novel c-Met inhibitor, suppresses the proliferation of lung cancer cells by downregulating the PI3K/AKT/mTOR and MAPK signaling pathways.
Yu, Jiaojiao; Zhang, Lijing; Peng, Jun; Ward, Richard; Hao, Peiqi; Wang, Jiwei; Zhang, Na; Yang, Yang; Guo, Xiaoxi; Xiang, Cheng; An, Su; Xu, Tian-Rui.
Afiliação
  • Yu J; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Zhang L; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Peng J; Department of Thoracic Surgery, the First People's Hospital of Yunnan Province, Kunming 650032, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China.
  • Ward R; Centre for Translational Pharmacology, Institute of Molecular Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
  • Hao P; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Wang J; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Zhang N; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Yang Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Guo X; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Xiang C; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • An S; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China; State Key Laboratory of Primate Biomedical Research, Kunming University of Science and Technology, Kunming 650500, China. Electronic address: aslxj@mail.ustc.edu.cn.
  • Xu TR; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China; State Key Laboratory of Primate Biomedical Research, Kunming University of Science and Technology, Kunming 650500, China. Electronic address: tianruixu@kust.edu.cn.
Biochem Pharmacol ; 195: 114864, 2022 01.
Article em En | MEDLINE | ID: mdl-34861243
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfotransferases / Quinolinas / Proteínas Proto-Oncogênicas c-met / Sistema de Sinalização das MAP Quinases / Proliferação de Células / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfotransferases / Quinolinas / Proteínas Proto-Oncogênicas c-met / Sistema de Sinalização das MAP Quinases / Proliferação de Células / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China