Liquid profiling of circulating tumor DNA in colorectal cancer: steps needed to achieve its full clinical value as standard care.

Hedtke, Maren; Pessoa Rejas, Rodrigo; Froelich, Matthias F; Ast, Volker; Duda, Angelika; Mirbach, Laura; Costina, Victor; Martens, Uwe M; Hofheinz, Ralf-Dieter; Neumaier, Michael; Haselmann, Verena

Hedtke, Maren; Pessoa Rejas, Rodrigo; Froelich, Matthias F; Ast, Volker; Duda, Angelika; Mirbach, Laura; Costina, Victor; Martens, Uwe M; Hofheinz, Ralf-Dieter; Neumaier, Michael; Haselmann, Verena.

Afiliação

Hedtke M; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Pessoa Rejas R; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Froelich MF; Department of Radiology and Nuclear Medicine, University Medicine Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Germany.
Ast V; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Duda A; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Mirbach L; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Costina V; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Martens UM; Cancer Center Heilbronn-Franken, SLK-Clinics, MOLIT Institute for Personalized Medicine, Heilbronn, Germany.
Hofheinz RD; Day Treatment Center (TTZ), Interdisciplinary Tumor Center Mannheim (ITM), III Medical Clinic, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Neumaier M; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.
Haselmann V; Institute of Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Germany.

Mol Oncol ; 16(10): 2042-2056, 2022 05.

Article em En | MEDLINE | ID: mdl-34873826

Assuntos

DNA Tumoral Circulante; Neoplasias Colorretais; Biomarcadores Tumorais/genética; DNA Tumoral Circulante/genética; Neoplasias Colorretais/diagnóstico; Neoplasias Colorretais/genética; Neoplasias Colorretais/patologia; Humanos; Biópsia Líquida/métodos; Mutação/genética; Estudos Retrospectivos

Palavras-chave

colorectal cancer; ctDNA; liquid biopsy; liquid profiling; real-world

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / DNA Tumoral Circulante Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos

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