Understanding the influence of AMG 510 on the structure of KRAS<sup>G12C</sup> empowered by molecular dynamics simulation.

Li, Yu; Han, Lei; Zhang, Ziding

Understanding the influence of AMG 510 on the structure of KRAS^G12C empowered by molecular dynamics simulation.

Li, Yu; Han, Lei; Zhang, Ziding.

Afiliação

Li Y; State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.
Han L; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.
Zhang Z; Tianjin's Clinical Research Center for Cancer, Tianjin, China.

Comput Struct Biotechnol J ; 20: 1056-1067, 2022.

Article em En | MEDLINE | ID: mdl-35284050

Palavras-chave

AMG 510; KRASG12C; Molecular dynamic simulation; Principal component analysis; Resistant mutation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Comput Struct Biotechnol J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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