Transcriptome Analyses of Adipose Tissue Samples Identify <i>EGFL6</i> as a Candidate Gene Involved in Obesity-Related Adipose Tissue Dysfunction in Children.

Landgraf, Kathrin; Kühnapfel, Andreas; Schlanstein, Maria; Biemann, Ronald; Isermann, Berend; Kempf, Elena; Kirsten, Holger; Scholz, Markus; Körner, Antje

Transcriptome Analyses of Adipose Tissue Samples Identify EGFL6 as a Candidate Gene Involved in Obesity-Related Adipose Tissue Dysfunction in Children.

Landgraf, Kathrin; Kühnapfel, Andreas; Schlanstein, Maria; Biemann, Ronald; Isermann, Berend; Kempf, Elena; Kirsten, Holger; Scholz, Markus; Körner, Antje.

Afiliação

Landgraf K; Center for Pediatric Research Leipzig (CPL), Hospital for Children & Adolescents, Leipzig University, 04103 Leipzig, Germany.
Kühnapfel A; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, 04107 Leipzig, Germany.
Schlanstein M; Center for Pediatric Research Leipzig (CPL), Hospital for Children & Adolescents, Leipzig University, 04103 Leipzig, Germany.
Biemann R; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig University, 04103 Leipzig, Germany.
Isermann B; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig University, 04103 Leipzig, Germany.
Kempf E; Center for Pediatric Research Leipzig (CPL), Hospital for Children & Adolescents, Leipzig University, 04103 Leipzig, Germany.
Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, 04107 Leipzig, Germany.
Scholz M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, 04107 Leipzig, Germany.
Körner A; LIFE Research Center for Civilization Diseases, Leipzig University, 04103 Leipzig, Germany.

Int J Mol Sci ; 23(8)2022 Apr 14.

Article em En | MEDLINE | ID: mdl-35457174

Assuntos

Tecido Adiposo; Leptina; Adipócitos/metabolismo; Tecido Adiposo/metabolismo; Proteínas de Ligação ao Cálcio/genética; Proteínas de Ligação ao Cálcio/metabolismo; Moléculas de Adesão Celular/metabolismo; Criança; Perfilação da Expressão Gênica; Humanos; Leptina/genética; Leptina/metabolismo; Obesidade/metabolismo

Palavras-chave

EGFL6; adipocyte; adipocyte hypertrophy; adipose tissue; adipose tissue dysfunction; children; metabolic disease; obesity; transcriptome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Leptina Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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