Single-cell RNA sequencing in silent corticotroph tumors confirms impaired POMC processing and provides new insights into their invasive behavior.

Zhang, Dongyun; Hugo, Willy; Bergsneider, Marvin; Wang, Marilene B; Kim, Won; Vinters, Harry V; Heaney, Anthony P

Zhang, Dongyun; Hugo, Willy; Bergsneider, Marvin; Wang, Marilene B; Kim, Won; Vinters, Harry V; Heaney, Anthony P.

Afiliação

Zhang D; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Hugo W; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Bergsneider M; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Wang MB; Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Kim W; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Vinters HV; Department of Pathology and Lab Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Heaney AP; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

Eur J Endocrinol ; 187(1): 49-64, 2022 May 12.

Article em En | MEDLINE | ID: mdl-35521707

Assuntos

Corticotrofos; Neoplasias Hipofisárias; Corticotrofos/metabolismo; Humanos; Neoplasias Hipofisárias/patologia; Pró-Opiomelanocortina/genética; Pró-Opiomelanocortina/metabolismo; Análise de Sequência de RNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Hipofisárias / Corticotrofos Limite: Humans Idioma: En Revista: Eur J Endocrinol Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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