Co-exposure to polystyrene microplastics and lead aggravated ovarian toxicity in female mice via the PERK/eIF2&#945; signaling pathway.

Feng, Yueying; Yuan, Hongbin; Wang, Wanzhen; Xu, Yuanyuan; Zhang, Jinfeng; Xu, Hengyi; Fu, Fen

Co-exposure to polystyrene microplastics and lead aggravated ovarian toxicity in female mice via the PERK/eIF2α signaling pathway.

Feng, Yueying; Yuan, Hongbin; Wang, Wanzhen; Xu, Yuanyuan; Zhang, Jinfeng; Xu, Hengyi; Fu, Fen.

Afiliação

Feng Y; The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang 330000, China; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Yuan H; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Wang W; The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang 330000, China; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Xu Y; The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang 330000, China.
Zhang J; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Xu H; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China. Electronic address: kidyxu@163.com.
Fu F; The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang 330000, China. Electronic address: fu_fen@163.com.

Ecotoxicol Environ Saf ; 243: 113966, 2022 Sep 15.

Article em En | MEDLINE | ID: mdl-35981484

Assuntos

Microplásticos; Poliestirenos; Animais; Fator de Iniciação 2 em Eucariotos/metabolismo; Feminino; Chumbo/toxicidade; Mamíferos/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Ovário/metabolismo; Plásticos; Poliestirenos/metabolismo; Poliestirenos/toxicidade; Transdução de Sinais

Palavras-chave

Combined exposure; Ovarian toxicity; Oxidative stress; PERK/eIF2α signaling pathway; PS-MPs; Pb

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliestirenos / Microplásticos Limite: Animals Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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