Targeting NR1H/liver X receptor with dendrogenin A differentiates tumor cells to activate a new secretory pathway releasing immunogenic anti-tumor vesicles enriched in LC3-II-associated exosomes.

de Medina, Philippe; Bunay, Julio; Poirot, Marc; Record, Michel; Silvente-Poirot, Sandrine

de Medina, Philippe; Bunay, Julio; Poirot, Marc; Record, Michel; Silvente-Poirot, Sandrine.

Afiliação

de Medina P; Team INOV, Cancer Research Center of Toulouse, UMR 1037 INSERM-UMR 5071 CNRS, University of Toulouse III, 2 avenue H. Curien 31037, Toulouse, France.
Bunay J; Team INOV, Cancer Research Center of Toulouse, UMR 1037 INSERM-UMR 5071 CNRS, University of Toulouse III, 2 avenue H. Curien 31037, Toulouse, France.
Poirot M; Team INOV, Cancer Research Center of Toulouse, UMR 1037 INSERM-UMR 5071 CNRS, University of Toulouse III, 2 avenue H. Curien 31037, Toulouse, France.
Record M; Team INOV, Cancer Research Center of Toulouse, UMR 1037 INSERM-UMR 5071 CNRS, University of Toulouse III, 2 avenue H. Curien 31037, Toulouse, France.
Silvente-Poirot S; Team INOV, Cancer Research Center of Toulouse, UMR 1037 INSERM-UMR 5071 CNRS, University of Toulouse III, 2 avenue H. Curien 31037, Toulouse, France.

Autophagy ; 19(3): 1036-1038, 2023 03.

Article em En | MEDLINE | ID: mdl-36063487

Assuntos

Exossomos; Neoplasias; Humanos; Receptores X do Fígado/metabolismo; Exossomos/metabolismo; Via Secretória; Autofagia; Neoplasias/metabolismo

Palavras-chave

Cancer; LC3; LXR; exosome; immunotherapy; oxysterol

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exossomos / Neoplasias Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Autophagy Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google