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1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation.
Pecoraro, Camilla; De Franco, Michele; Carbone, Daniela; Bassani, Davide; Pavan, Matteo; Cascioferro, Stella; Parrino, Barbara; Cirrincione, Girolamo; Dall'Acqua, Stefano; Moro, Stefano; Gandin, Valentina; Diana, Patrizia.
Afiliação
  • Pecoraro C; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, via Archirafi 32, 90123, Palermo, Italy.
  • De Franco M; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via F. Marzolo 5, 35131, Padova, Italy.
  • Carbone D; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, via Archirafi 32, 90123, Palermo, Italy.
  • Bassani D; Department of Pharmaceutical and Pharmacological Sciences, Molecular Modeling Section (MMS), University of Padova, via F. Marzolo 5, 35131, Padova, Italy.
  • Pavan M; Department of Pharmaceutical and Pharmacological Sciences, Molecular Modeling Section (MMS), University of Padova, via F. Marzolo 5, 35131, Padova, Italy.
  • Cascioferro S; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, via Archirafi 32, 90123, Palermo, Italy.
  • Parrino B; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, via Archirafi 32, 90123, Palermo, Italy.
  • Cirrincione G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, via Archirafi 32, 90123, Palermo, Italy.
  • Dall'Acqua S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via F. Marzolo 5, 35131, Padova, Italy.
  • Moro S; Department of Pharmaceutical and Pharmacological Sciences, Molecular Modeling Section (MMS), University of Padova, via F. Marzolo 5, 35131, Padova, Italy.
  • Gandin V; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via F. Marzolo 5, 35131, Padova, Italy. Electronic address: valentina.gandin@unipd.it.
  • Diana P; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, via Archirafi 32, 90123, Palermo, Italy. Electronic address: patrizia.diana@unipa.it.
Eur J Med Chem ; 249: 115134, 2023 Mar 05.
Article em En | MEDLINE | ID: mdl-36709650
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proteínas Serina-Treonina Quinases Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proteínas Serina-Treonina Quinases Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália