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Accurate detection of reactive oxygen species by tuning an elastic motif (GPGGA)4 in nanopores.
Wang, Cunli; Yang, Yiming; Shao, Shuai; Zhang, Hangyu; Li, Na; Zhang, Zhengyao; Liu, Bo.
Afiliação
  • Wang C; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
  • Yang Y; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
  • Shao S; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
  • Zhang H; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
  • Li N; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
  • Zhang Z; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
  • Liu B; School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian, 116024, P. R. China. lbo@dlut.edu.cn.
Chem Commun (Camb) ; 59(29): 4368-4371, 2023 Apr 06.
Article em En | MEDLINE | ID: mdl-36946304
We have developed a reactive oxygen species (ROS) sensor based on nanopores modified with GGGCEG(GPGGA)4CEG. The formation of an intramolecular disulfide bond oxidized by ROS leads to conformation changes in GGGCEG(GPGGA)4CEG, which then induces an obvious change in the size of the nanopores and a corresponding ionic current change. This work allows the accurate and dynamic monitoring of ROS through the combination of (GPGGA)4 and nanopores.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de publicação: Reino Unido