A convolutional neural network-based model that predicts acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

Jo, Tomoyasu; Arai, Yasuyuki; Kanda, Junya; Kondo, Tadakazu; Ikegame, Kazuhiro; Uchida, Naoyuki; Doki, Noriko; Fukuda, Takahiro; Ozawa, Yukiyasu; Tanaka, Masatsugu; Ara, Takahide; Kuriyama, Takuro; Katayama, Yuta; Kawakita, Toshiro; Kanda, Yoshinobu; Onizuka, Makoto; Ichinohe, Tatsuo; Atsuta, Yoshiko; Terakura, Seitaro

Jo, Tomoyasu; Arai, Yasuyuki; Kanda, Junya; Kondo, Tadakazu; Ikegame, Kazuhiro; Uchida, Naoyuki; Doki, Noriko; Fukuda, Takahiro; Ozawa, Yukiyasu; Tanaka, Masatsugu; Ara, Takahide; Kuriyama, Takuro; Katayama, Yuta; Kawakita, Toshiro; Kanda, Yoshinobu; Onizuka, Makoto; Ichinohe, Tatsuo; Atsuta, Yoshiko; Terakura, Seitaro.

Afiliação

Jo T; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Arai Y; Center for Research and Application of Cellular Therapy, Kyoto University Hospital, Kyoto, Japan.
Kanda J; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ysykrai@kuhp.kyoto-u.ac.jp.
Kondo T; Center for Research and Application of Cellular Therapy, Kyoto University Hospital, Kyoto, Japan. ysykrai@kuhp.kyoto-u.ac.jp.
Ikegame K; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Uchida N; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Doki N; Department of Hematology, Hyogo Medical University Hospital, Hyogo, Japan.
Fukuda T; Department of Hematology, Federation of National Public Service Personnel Mutual Aid Associations Toranomon Hospital, Tokyo, Japan.
Ozawa Y; Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
Tanaka M; Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Ara T; Department of Hematology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan.
Kuriyama T; Department of Hematology, Kanagawa Cancer Center, Yokohama, Japan.
Katayama Y; Department of Hematology, Hokkaido University Hospital, Sapporo, Japan.
Kawakita T; Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
Kanda Y; Department of Hematology, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan.
Onizuka M; Department of Hematology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan.
Ichinohe T; Division of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Atsuta Y; Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Japan.
Terakura S; Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.

Commun Med (Lond) ; 3(1): 67, 2023 May 16.

Article em En | MEDLINE | ID: mdl-37193882

Hematopoietic stem cell transplantation (HSCT) is a procedure used in patients to reestablish blood cell production. It involves the transplant of cells from a donor to the patient. In some patients the transplanted cells damage cells within the patients. This is called graft-versus-host disease (GVHD). We developed a computational code that can predict the likelihood a person will develop GVHD soon after HSCT. Using this computer program will enable doctors to better identify those at risk of GVHD and initiate treatments when required.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Commun Med (Lond) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido

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