Sinomenine Ameliorates IL-1ß-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-&#954;B Signaling Pathways.

Lu, Gongbiao; Zhang, Cunxin; Li, Kang; Gao, Kai; Fu, Maoqing; Lyu, Chaoliang; Quan, Zhengxue

Sinomenine Ameliorates IL-1ß-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-κB Signaling Pathways.

Lu, Gongbiao; Zhang, Cunxin; Li, Kang; Gao, Kai; Fu, Maoqing; Lyu, Chaoliang; Quan, Zhengxue.

Afiliação

Lu G; Department of Spine Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400042, People's Republic of China.
Zhang C; Department of Spine Surgery, Jining No.1 People's Hospital, Jining, 272011, People's Republic of China.
Li K; Department of Spine Surgery, Jining No.1 People's Hospital, Jining, 272011, People's Republic of China.
Gao K; Department of Spine Surgery, Jining No.1 People's Hospital, Jining, 272011, People's Republic of China.
Fu M; Department of Orthopaedics, Jining No.1 People's Hospital, Jining, 272011, People's Republic of China.
Lyu C; Department of Spine Surgery, Jining No.1 People's Hospital, Jining, 272011, People's Republic of China.
Quan Z; Department of Spine Surgery, Jining No.1 People's Hospital, Jining, 272011, People's Republic of China.

J Inflamm Res ; 16: 4777-4791, 2023.

Article em En | MEDLINE | ID: mdl-37881650

Palavras-chave

NF-κB; Nrf2; apoptosis; intervertebral disc degeneration; nucleus pulposus cells; sinomenine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Inflamm Res Ano de publicação: 2023 Tipo de documento: Article