Immunological processes of enhancers and suppressors of long non-coding RNAs associated with brain tumors and inflammation.

Immunological processes, such as inflammation, can both cause tumor suppression and cancer progression. Long non-coding RNA (lncRNA) expression in the brain may cause inflammation and lead to the growth of tumors. LncRNAs have the potential to influence carcinogenesis, tumor formation, or tumor suppression via an increase or decrease in inflammation functions. However, there are limitations and challenges to the study and targeting of lncRNAs. New targeting technologies, such as nanocarriers and cell-penetrating peptides (CPPs), may be used to target brain cancer without hurting healthy body tissues.