A case report of lymphoproliferative disease in brain following therapies with mycophenolate Mofetil and Fingolimod and literature review.
J Neuroimmunol
; 394: 578410, 2024 09 15.
Article
em En
| MEDLINE
| ID: mdl-39067241
ABSTRACT
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder. With the method of indirect immunofluorescence assay (IIF), more anti-NMDAR encephalitis patients have been discovered when its first onset. But it was rare that anti-NMDAR encephalitis overlapped with multiple sclerosis (MS) documented in literatures. Here, we present a case who initially developed anti-NMDAR encephalitis and MS. Furthermore, we concluded the characteristics of patients who were diagnosed as anti-NMDAR encephalitis overlapping with MS. Additionally, due to the relapsing process, mycophenolate mofetil and sequentially fingolimod for the treatment were taken, which subsequently led to the development of a lymphoproliferative disease in his brain and other organs. This case illustrates the complex role of immunosuppressive agents.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cloridrato de Fingolimode
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Imunossupressores
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Transtornos Linfoproliferativos
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Ácido Micofenólico
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
J Neuroimmunol
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J. neuroimmunol
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Journal of neuroimmunology
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Holanda