A case report of acute Q fever with low-read detection of Coxiella burnetii genome by next-generation metagenomic sequencing.

Wu, Xianglin; Xu, Aohong; Tian, Feng; Yang, Juhong; Lin, Liekun; Zhai, Mingzhu; Wu, Benqing; Zheng, Yi

Wu, Xianglin; Xu, Aohong; Tian, Feng; Yang, Juhong; Lin, Liekun; Zhai, Mingzhu; Wu, Benqing; Zheng, Yi.

Afiliação

Wu X; Department of Laboratory Medicine, Shenzhen Guangming District People's Hospital, Shenzhen, Guangdong, China.
Xu A; Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China.
Tian F; Department of Laboratory Medicine, Shenzhen Guangming District People's Hospital, Shenzhen, Guangdong, China.
Yang J; Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China.
Lin L; Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China.
Zhai M; Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China.
Wu B; Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China.
Zheng Y; Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China. Electronic address: zhengyi1205@126.com.

Diagn Microbiol Infect Dis ; 110(2): 116434, 2024 Oct.

Article em En | MEDLINE | ID: mdl-39111107

ABSTRACT

ABSTRACT

The case presents a 47-year-old man with sudden abdominal pain and fever, but the cause was uncertain. Through metagenomic next-generation sequencing (mNGS) and detecting Q fever antibodies in serum, along with the patient's clinical and epidemiological history, a precise diagnosis was made, enabling timely and proper treatment.

Assuntos

Coxiella burnetii; Sequenciamento de Nucleotídeos em Larga Escala; Metagenômica; Febre Q; Humanos; Coxiella burnetii/genética; Coxiella burnetii/isolamento & purificação; Masculino; Febre Q/diagnóstico; Febre Q/microbiologia; Pessoa de Meia-Idade; Metagenômica/métodos; Genoma Bacteriano/genética; Anticorpos Antibacterianos/sangue

Palavras-chave

Coxiella burnetii; Metagenomic next-generation sequencing(mNGS); Q fever

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Febre Q / Coxiella burnetii / Metagenômica / Sequenciamento de Nucleotídeos em Larga Escala Limite: Humans / Male / Middle aged Idioma: En Revista: Diagn Microbiol Infect Dis / Diagn. microbiol. infect. dis / Diagnostic microbiology and infectious disease Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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