Rapid brain lymphoma diagnostics through nanopore sequencing of cytology-negative cerebrospinal fluid.

Hench, J; Hultschig, C; Bratic Hench, I; Sadasivan, H; Yaldizli, Ö; Hutter, G; Dirnhofer, S; Tzankov, A; Frank, S

Hench, J; Hultschig, C; Bratic Hench, I; Sadasivan, H; Yaldizli, Ö; Hutter, G; Dirnhofer, S; Tzankov, A; Frank, S.

Afiliação

Hench J; Institute for Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland. jurgen.hench@gmail.com.
Hultschig C; Institute for Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland.
Bratic Hench I; Institute for Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland.
Sadasivan H; AI Group, AMD and Paul G Allen School of CSE, University of Washington, Seattle, USA.
Yaldizli Ö; Dept. of Neurology, University Hospital Basel, Basel, Switzerland.
Hutter G; Dept. of Neurosurgery, University Hospital Basel, Basel, Switzerland.
Dirnhofer S; Institute for Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland.
Tzankov A; Institute for Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland.
Frank S; Institute for Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland.

Acta Neuropathol ; 148(1): 36, 2024 Sep 03.

Article em En | MEDLINE | ID: mdl-39225884

Assuntos

Neoplasias Encefálicas; Humanos; Neoplasias Encefálicas/líquido cefalorraquidiano; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/diagnóstico; Neoplasias Encefálicas/patologia; Sequenciamento por Nanoporos/métodos; Masculino; Linfoma/líquido cefalorraquidiano; Linfoma/diagnóstico; Linfoma/patologia; Linfoma/genética; Feminino; Pessoa de Meia-Idade; Idoso; Citologia

Palavras-chave

CNS lymphoma; DNA methylation; Epigenetics; Liquid biopsy; Nanopore sequencing; Non-invasive diagnostics; Point-of-care testing; Rapid testing; Tumor classification; Unsupervised machine learning

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neuropathol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Suíça País de publicação: Alemanha

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