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Pathogenesis, diagnostics, and therapeutics for Alzheimer's disease: Breaking the memory barrier.
Kamatham, Pushpa Tryphena; Shukla, Rashi; Khatri, Dharmendra Kumar; Vora, Lalitkumar K.
Afiliação
  • Kamatham PT; Molecular and Cellular Neuroscience Laboratory, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana 500037, India.
  • Shukla R; Molecular and Cellular Neuroscience Laboratory, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana 500037, India.
  • Khatri DK; Department of Pharmacology, Nims Institute of Pharmacy, Nims University Rajasthan, Jaipur, India. Electronic address: dkkhatri10@gmail.com.
  • Vora LK; School of Pharmacy, Medical Biology Centre, Queen's University Belfast, 97 Lisburn Road, Belfast, Northern Ireland BT9 7BL, UK. Electronic address: L.Vora@qub.ac.uk.
Ageing Res Rev ; 101: 102481, 2024 Sep 03.
Article em En | MEDLINE | ID: mdl-39236855
ABSTRACT
Alzheimer's disease (AD) is the most common cause of dementia and accounts for 60-70 % of all cases. It affects millions of people worldwide. AD poses a substantial economic burden on societies and healthcare systems. AD is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. As the prevalence of AD continues to increase, understanding its pathogenesis, improving diagnostic methods, and developing effective therapeutics have become paramount. This comprehensive review delves into the intricate mechanisms underlying AD, explores the current state of diagnostic techniques, and examines emerging therapeutic strategies. By revealing the complexities of AD, this review aims to contribute to the growing body of knowledge surrounding this devastating disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Ageing Res Rev / Ageing res. rev / Ageing research reviews Assunto da revista: GERIATRIA Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Ageing Res Rev / Ageing res. rev / Ageing research reviews Assunto da revista: GERIATRIA Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido