A controlled study of morbidity of Schistosomiasis mansoni in St. Lucian children, based on quantitative egg excretion
Am J Trop Med Hyg
; 23(4): 625-33, July 1974.
Artigo
em Inglês
| MedCarib
| ID: med-13050
Biblioteca responsável:
JM3.1
Localização: JM3.1; RC960.A42
ABSTRACT
A study of the morbidity of schistosomiasis mansoni was made in 138 schoolchildren (age range, 7-16 years) in St. Lucia. The study was based on quantitative egg excretion data collected over a 4-year period before the study and included a comparable uninfected control group. All examinations were carried out "blind". Infected subjects were divided into three levels of intensity of infection heavy, 400 or more eggs/ml of feces; moderate, 100 to 300 eggs/ml; and light, 10 to 75 eggs/ml. The children were hospitalized for medical histories and physical and laboratory examinations. Gastrointestinal symptoms were present at relatively high levels in all groups, and were more frequent in the Schistosoma mansoni-infected subjects than in the controls. Anthropometric measurements showed no differences between the groups. Hepatomegaly and splenomegaly were significantly more frequent in the heavy-moderate infection group, and extension of the liver below the coastal margin was found to increase with intensity of infection; serum albumin level was inversely related. It was clear that in this St. Lucian study, infection with S. mansoni did not result in disease in most of the school-age subjects investigated; assessment of possible long-term(>4 years) effects was not made. This study provides a method for assessing morbidity of schistosomiasis based on quantitative egg excretion and demonstrates the relation of objective morbidity to intensity of infection.(AU)
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Helmintíase
/
Doenças Negligenciadas
/
Esquistossomose
/
Zoonoses
Base de dados:
MedCarib
Assunto principal:
Schistosoma mansoni
/
Esquistossomose
/
Enteropatias Parasitárias
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
Limite:
Adolescente
/
Criança
/
Humanos
País/Região como assunto:
Caribe Inglês
/
Santa Lúcia
Idioma:
Inglês
Revista:
Am J Trop Med Hyg
Ano de publicação:
1974
Tipo de documento:
Artigo