A comparison of the adhesion-barrier interceed (free), interceed (fixed) and Ringer's lactate in the prevention of post-operative adhesion formation - abstract

ABSTRACT

Forty white rats were randomly assigned into four groups in which a standardized adhesion-forming lesion was created at laparotomy. Attempts to prevent adhesion formation were made in the presence of an artificial adhesion barrier, Interceed (free or fixed with 6/0 vicryl sutures) and Ringer's lactate versus a control group. Interceed freely placed on the site resulted in either very low or very high adhesion scores. This suggests that Interceed is an effective adhesion barrier but that a method which does not itself create tissue reaction must be devised to keep the barrier in place. Further research into an appropriate "tissue glue" is required (AU)