Fasting plasma insulin and C-peptide levels in pre-eclampsia - abstract

ABSTRACT

In this study, plasma insulin, C-peptide and glucose measurements were done on the fasting blood samples obtained from primigravid pre-eclamptic (PE) women and suitably matched normal pregnant (NP) controls. This was done in order to observe any differences in the pancreatic secretion of insulin between these two groups. Fasting hyperinsulinaemia was observed as a statistically significant feature in the PE. The fasting C-peptide and glucose levels were not significantly different between the two groups. From the fasting C-peptide levels observed it would appear that the hyperinsulinaemia observed in the PE was not the result of hypersecretion of insulin by the pancreas (AU)